Skip to content

LMP Hematopathologist publishes leukemia workshop in the American Journal for Clinical Pathology

August 21, 2015

Dr. Porwit 02


Recently, Dr. Anna Porwit, Hematopathologist, Laboratory Medicine Program (LMP) had her work on mixed-phenotype acute leukemia (MPAL) published in the American Journal for Clinical Pathology. The study is part of a workshop series by the Society for Hematopathology/European Association for Haematopathology and summarizes diagnostic criteria for major types of MPAL.

There were 32 cases included in this session of the workshop, and the publication illustrates and describes the variability of MPAL, the technical issues involved in diagnosis, and how cases can be linked by common characteristics.

More detailed, the study discusses: technical issues in determining blast lineage, possible pitfalls in MPAL diagnosis, and the differential diagnosis between acute undifferentiated leukemia and acute myeloid leukemia with minimal differentiation.

The study emphasizes the need for: flow cytometry immunophenotyping using a large panel of antibodies, as well as confirmatory immunohistochemical analysis and cytochemistry studies to accurately establish the diagnosis of MPAL.


For more information see: HERE

One Comment leave one →
  1. Mina J. permalink
    August 27, 2015 4:29 pm

    Congrats, Anna … excellent workshop session and publication.
    Thanks for sharing, UHN path report.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s